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Tg(Thy1-Snca)1S13Putt
Transgene Detail
Nomenclature
Symbol: Tg(Thy1-Snca)1S13Putt
Name: transgene insertion 1S13, Herman van der Putten
MGI ID: MGI:5573194
Synonyms: Thy1-malphaSN
Transgene: Tg(Thy1-Snca)1S13Putt  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Thy1-Snca)1S13Putt expresses 1 gene
 
Mutation detailsWild-type mouse alpha-synuclein cDNA expression is driven by the Thy1 regulatory sequences. Three lines were created: 1S13, 1S14, and 1S16. This line expresses mRNA and protein levels in the brain that are up to 6-fold above endogenous levels. (J:177661)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:177661 Rieker C, et al., Neuropathology in mice expressing mouse alpha-synuclein. PLoS One. 2011;6(9):e24834
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory