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Tg(Cnp-MAPT*P301L)6Vle
Transgene Detail
Nomenclature
Symbol: Tg(Cnp-MAPT*P301L)6Vle
Name: transgene insertion 6, Virginia M Y Lee
MGI ID: MGI:5573156
Synonyms: Tau CNP Tg
Transgene: Tg(Cnp-MAPT*P301L)6Vle  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe murine 2', 3'-cyclic nucleotide 3'-phosphodiesterase promoter drives expression of the P301L mutant human microtubule-associated protein tau, MAPT. Immunohistochemistry confirmed expression in oligodendrocytes. (J:127923)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:127923 Giasson BI, et al., Initiation and synergistic fibrillization of tau and alpha-synuclein. Science. 2003 Apr 25;300(5619):636-40
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory