About   Help   FAQ
Tg(tetO-MYCN,-luc)#Waw
Transgene Detail
Nomenclature
Symbol: Tg(tetO-MYCN,-luc)#Waw
Name: transgene insertion, William A Weiss
MGI ID: MGI:5570746
Synonyms: TML, TRE-MYCN/Luc
Transgene: Tg(tetO-MYCN,-luc)#Waw  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Tg(tetO-MYCN,-luc)#Waw expresses 1 gene
 
Mutation detailsThe bi-directional tetracycline-responsive operator drives inducible expression of the human MYCN cDNA and firefly luciferase. In double transgenic mice also expressing the tetracycline transactivating or reverse transactivating element (tTA or rtTA), expression of MYCN can be regulated by doxycycline administration or removal. (J:160518)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:160518 Swartling FJ, et al., Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15;24(10):1059-72
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/30/2021
MGI 6.16
The Jackson Laboratory