Dcbld2tm1Mhms
Targeted Allele Detail
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Symbol: |
Dcbld2tm1Mhms |
Name: |
discoidin, CUB and LCCL domain containing 2; targeted mutation 1, Mehran M Sadeghi |
MGI ID: |
MGI:5569303 |
Synonyms: |
Esdnfl |
Gene: |
Dcbld2 Location: Chr16:58228806-58290090 bp, + strand Genetic Position: Chr16, 34.52 cM, cytoband C1.1
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Alliance: |
Dcbld2tm1Mhms page
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Decreased retinal angiogenesis in Dcbld2tm1Mhms/Dcbld2tm1.1Mhms Tg(Cdh5-cre)7Mlia/0 mice
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:207629
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Parent Cell Line: |
TC1/TC-1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 1. A floxed neomycin resistance cassette was inserted downstream of exon 1.
(J:207629)
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Generation of the Dcbld2tm1Mhms and Dcbld2tm1.1Mhms alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Dcbld2 Mutation: |
47 strains or lines available
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Original: |
J:207629 Nie L, et al., Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenesis. J Clin Invest. 2013 Dec 2;123(12):5082-97 |
All: |
2 reference(s) |
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