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Tg(CAG-A4GALT)#Sais
Transgene Detail
Summary
Symbol: Tg(CAG-A4GALT)#Sais
Name: transgene insertion, Satoshi Ishii
MGI ID: MGI:5566993
Synonyms: Tg(CAG-A4GALT), TgG3s
Transgene: Tg(CAG-A4GALT)#Sais  Location: unknown  
Alliance: Tg(CAG-A4GALT)#Sais page
Transgene
origin
Strain of Origin:  C57BL/6JJms
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-A4GALT)#Sais expresses 1 gene
 
Mutation detailsThis transgene consists of the human alpha 1,4-galactosyltransferase cDNA driven by the CAG promoter (from expression vector expression vector pCXN2). RT-PCR confirmed expression in heart, kidney, liver, spleen, small intestine, brain, lungs and muscle. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:209274)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:209274 Shiozuka C, et al., Increased globotriaosylceramide levels in a transgenic mouse expressing human alpha1,4-galactosyltransferase and a mouse model for treating Fabry disease. J Biochem. 2011 Feb;149(2):161-70
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory