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Zic2em1Bend
Endonuclease-mediated Allele Detail
Summary
Symbol: Zic2em1Bend
Name: zinc finger protein of the cerebellum 2; endonuclease-mediated mutation 1, Ben Davies
MGI ID: MGI:5566852
Synonyms: BL6-1
Gene: Zic2  Location: Chr14:122712847-122717264 bp, + strand  Genetic Position: Chr14, 65.97 cM
Alliance: Zic2em1Bend page
Curly tail in a Zic2em1Bend/Zic2+ founder

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutations:    Intragenic deletion, Single point mutation
 
Mutation detailsTALEN mediated recombination introduced a 2 bp deletion and a C to T mutation resulting in a frameshift mutation. (J:199882)
TALEN mediated recombination scheme used to generate the Zic2em1Bend, Zic2em2Bend, Zic2em3Bend, Zic2em4Bend and Zic2em5Bend alleles
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zic2 Mutation:  41 strains or lines available
References
Original:  J:199882 Davies B, et al., Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes. PLoS One. 2013;8(3):e60216
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory