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Agxt2tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Agxt2tm1Lex
Name: alanine-glyoxylate aminotransferase 2; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:5560668
Gene: Agxt2  Location: Chr15:10358532-10410153 bp, + strand  Genetic Position: Chr15, 5.35 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:207876
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    The beta-geo and puromycin resistance cassette replaced exons 8 and 9. (J:207876)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Agxt2 Mutation:  17 strains or lines available
References
Original:  J:207876 Caplin B, et al., Alanine-glyoxylate aminotransferase-2 metabolizes endogenous methylarginines, regulates NO, and controls blood pressure. Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2892-900
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory