Tjp1^tm1Tlch
Targeted Allele Detail

Summary

• Symbol: Tjp1^tm1Tlch
• Name: tight junction protein 1; targeted mutation 1, Terry Lechler
• MGI ID: MGI:5558017
• Synonyms: ZO-1-GFP
• Gene: Tjp1 Location: Chr7:64945913-65177529 bp, - strand Genetic Position: Chr7, 35.02 cM
• Alliance: Tjp1^tm1Tlch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205841
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• A knock-in allele was generated to carboxy-terminal tag the endogenous coding sequence with GFP. (J:205841)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tjp1 Mutation: 66 strains or lines available

References

• Original: J:205841 Foote HP, et al., FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes. PLoS One. 2013;8(8):e71491
• All: 4 reference(s)