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Tg(Ckm-Pnpla2)164Eek
Transgene Detail
Nomenclature
Symbol: Tg(Ckm-Pnpla2)164Eek
Name: transgene insertion 164, Erin E Kershaw
MGI ID: MGI:5554433
Synonyms: Ckm-ATGL
Transgene: Tg(Ckm-Pnpla2)164Eek  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ckm-Pnpla2)164Eek expresses 1 gene
 
Mutation detailsA modified creatine kinase muscle specific promoter drives expression of the full length Pnpla2 cDNA including 418 bp of 3' sequence containing the polyA signal. The modified promoter contains the murine Ckm promoter and enhancer E1, untranslated exon 1, intron 1 including enhancer E2, the first 16 bp of exon 2 and an SV40 polyA signal. Several lines were generated including: 1 and 164. This is a representative record for both lines. (J:207007)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:207007 Sitnick MT, et al., Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes. 2013 Oct;62(10):3350-61
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory