Ifngr1^tm1Dmer
Targeted Allele Detail

Summary

• Symbol: Ifngr1^tm1Dmer
• Name: interferon gamma receptor 1; targeted mutation 1, Doron Merkler
• MGI ID: MGI:5552972
• Synonyms: IFNGR^fl
• Gene: Ifngr1 Location: Chr10:19467697-19485977 bp, + strand Genetic Position: Chr10, 8.49 cM
• Alliance: Ifngr1^tm1Dmer page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202844
• Parent Cell Line: IDG3.2 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 4 through 6 were floxed. (J:202844)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ifngr1 Mutation: 52 strains or lines available

References

• Original: J:202844 Kreutzfeldt M, et al., Neuroprotective intervention by interferon-gamma blockade prevents CD8+ T cell-mediated dendrite and synapse loss. J Exp Med. 2013 Sep 23;210(10):2087-103
• All: 1 reference(s)