Hspb1^tm1.1Mrl
Targeted Allele Detail

Summary

• Symbol: Hspb1^tm1.1Mrl
• Name: heat shock protein 1; targeted mutation 1.1, Merck Research Laboratory
• MGI ID: MGI:5551895
• Synonyms: hspB1^del
• Gene: Hspb1 Location: Chr5:135916773-135918417 bp, + strand Genetic Position: Chr5, 75.51 cM
• Alliance: Hspb1^tm1.1Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205424
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed the floxed sequence. (J:205424)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hspb1 Mutation: 18 strains or lines available

References

• Original: J:205424 McGuire VA, et al., Cross talk between the Akt and p38alpha pathways in macrophages downstream of Toll-like receptor signaling. Mol Cell Biol. 2013 Nov;33(21):4152-65
• All: 1 reference(s)