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Tg(Adipoq-cre/Esr1*)1Evdr
Transgene Detail
Nomenclature
Symbol: Tg(Adipoq-cre/Esr1*)1Evdr
Name: transgene insertion 1, Evan Rosen
MGI ID: MGI:5550467
Synonyms: Adiponectin-creER
Transgene: Tg(Adipoq-cre/Esr1*)1Evdr  Location: unknown  
Transgene
origin
Strain of Origin:  129
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsTo generate the Adipoq-cre/Esr1 BAC transgenic mice, the 245 kb RP23-90G21 bacterial artificial chromosome (BAC) containing at least five mouse genes was modified by replacing the starting ATG and 222 bp of the adiponectin gene with the starting ATG and sequence encoding the cre/ERT, cre recombinase and an estrogen receptor 1 (mouse) fusion gene. This modified BAC transgene was microinjected into fertilized 129 mouse eggs. Founder line 1 was subsequently established. (J:206506)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Adipoq     Summary of all recombinase alleles driven by Adipoq. Comparative matrix view of recombinase activities
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:206506 Rosen, et al., Generation of an inducible Adipoq-cre transgene. MGI Direct Data Submission. 2014;
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory