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Slc6a2tm1.1Hhg
Targeted Allele Detail
Nomenclature
Symbol: Slc6a2tm1.1Hhg
Name: solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2; targeted mutation 1.1, Haihua Gu
MGI ID: MGI:5547831
Synonyms: NET-CI
Gene: Slc6a2  Location: Chr8:93687100-93728295 bp, + strand  Genetic Position: Chr8, 44.99 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Nucleotide substitutions
 
Mutation detailsThe targeting construct was designed to insert a loxP-flanked neomycin (neo) resistance cassette downstream of exon 2. The double mutation, F101C/A105G, was introduced in exon 2 and a third mutation, N153T, was introduced into exon 3. Cre-mediated recombination removed the floxed neo cassette. (J:101977)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc6a2 Mutation:  25 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory