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Targeted Allele Detail
Symbol: Xcr1tm2(HBEGF/Venus)Ksho
Name: chemokine (C motif) receptor 1; targeted mutation 2, Tsuneyasu Kaisho
MGI ID: MGI:5544058
Synonyms: Xcr1DTRvenus
Gene: Xcr1  Location: Chr9:123681380-123691094 bp, - strand  Genetic Position: Chr9, 74.71 cM, cytoband F4
Alliance: Xcr1tm2(HBEGF/Venus)Ksho page
Germline Transmission:  Earliest citation of germline transmission: J:204851
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Allele Type:    Targeted (Humanized sequence, Inserted expressed sequence, Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA fusion of the human HBEGF (DTR; diphtheria toxin receptor) and Venus reporter followed by a loxP and FRT-flanked neomycin resistance cassette replaced the coding sequence. (J:204851)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Xcr1 Mutation:  25 strains or lines available
Original:  J:204851 Yamazaki C, et al., Critical roles of a dendritic cell subset expressing a chemokine receptor, XCR1. J Immunol. 2013 Jun 15;190(12):6071-82
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory