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Nmnat2Gt(EUCE0262a08)1.1Hmgu
Gene trapped Allele Detail
Nomenclature
Symbol: Nmnat2Gt(EUCE0262a08)1.1Hmgu
Name: nicotinamide nucleotide adenylyltransferase 2; gene trap EUCE0262a08, 1.1, Helmholtz Zentrum Muenchen GmbH
MGI ID: MGI:5543590
Synonyms: Nmnat2gt(inv)
Gene: Nmnat2  Location: Chr1:152954993-153119261 bp, + strand  Genetic Position: Chr1, 65.15 cM
Mutation
origin
Mutant Cell Line:  EUCE0262a08 (EUCOMM)
Germline Transmission:  Earliest citation of germline transmission: J:200901
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: rsFlipROSAbgeo*
 
Mutation detailsThe gene trap cassette is flanked with FRT, F3, loxP and lox511 sites. The sites are oriented to allow for inversion of the gene trap cassette. The gene trap construct inserted into intron 1. Flp mediated recombination inverted the trap cassette allowing for expression of the endogenous gene and removing one FRT and one F3 site. (J:200901)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nmnat2 Mutation:  267 strains or lines available
References
Original:  J:200901 Gilley J, et al., Rescue of Peripheral and CNS Axon Defects in Mice Lacking NMNAT2. J Neurosci. 2013 Aug 14;33(33):13410-24
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory