Nmnat2^{Gt(EUCE0262a08)1.1Hmgu}
Gene trapped Allele Detail

Summary

• Symbol: Nmnat2^{Gt(EUCE0262a08)1.1Hmgu}
• Name: nicotinamide nucleotide adenylyltransferase 2; gene trap EUCE0262a08, 1.1, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5543590
• Synonyms: Nmnat2^gt(inv)
• Gene: Nmnat2 Location: Chr1:152830744-152995007 bp, + strand Genetic Position: Chr1, 65.15 cM
• Alliance: Nmnat2^{Gt(EUCE0262a08)1.1Hmgu} page

Mutation origin

• Mutant Cell Line: EUCE0262a08
• Germline Transmission: Earliest citation of germline transmission: J:200901
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: rsFlipROSAbgeo*
• Mutation details: The gene trap cassette is flanked with FRT, F3, loxP and lox511 sites. The sites are oriented to allow for inversion of the gene trap cassette. The gene trap construct inserted into intron 1. Flp mediated recombination inverted the trap cassette allowing for expression of the endogenous gene and removing one FRT and one F3 site. (J:200901)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nmnat2 Mutation: 270 strains or lines available

References

• Original: J:200901 Gilley J, et al., Rescue of Peripheral and CNS Axon Defects in Mice Lacking NMNAT2. J Neurosci. 2013 Aug 14;33(33):13410-24
• All: 2 reference(s)