Tg(tetO-Dkk1)1Smr
Transgene Detail

Summary

• Symbol: Tg(tetO-Dkk1)1Smr
• Name: transgene insertion 1, Sarah E Millar
• MGI ID: MGI:5532849
• Synonyms: tetO-Dkk1
• Transgene: Tg(tetO-Dkk1)1Smr Location: unknown
• Alliance: Tg(tetO-Dkk1)1Smr page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL/J)F2

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: Mouse Dkk1 cDNA was subcloned into a vector containing a tetO promoter sequence. The construct was injected into fertilized (C57BL/6J x SJL/J)F2 oocytes. Founders were identified by Southern blot. Line information is not available. (J:98338)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:98338 Chu EY, et al., Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis. Development. 2004 Oct;131(19):4819-29
• All: 8 reference(s)