Kmt2b^Gena263
Chemically induced Allele Detail

Summary

• Symbol: Kmt2b^Gena263
• Name: lysine (K)-specific methyltransferase 2B; Gena263, Harwell
• MGI ID: MGI:5532297
• Synonyms: Mll2^M2628K
• Gene: Kmt2b Location: Chr7:30268283-30288151 bp, - strand Genetic Position: Chr7, 18.63 cM, cytoband A3
• Alliance: Kmt2b^Gena263 page

Mutation origin

• Strain of Origin: BALB/c

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A point mutation (c.7883T>A ENSMUST00000108154, NCBIM37) that results in the amino acid substitution of methionine with lysine at position 2628 (p.M2628K). (J:203736)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kmt2b Mutation: 63 strains or lines available

References

• Original: J:79719 Hough TA, et al., Novel phenotypes identified by plasma biochemical screening in the mouse. Mamm Genome. 2002 Oct;13(10):595-602
• All: 2 reference(s)