Adck2^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Adck2^{tm1.1(KOMP)Vlcg}
• Name: aarF domain containing kinase 2; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5529498
• Gene: Adck2 Location: Chr6:39550807-39565703 bp, + strand Genetic Position: Chr6, 18.39 cM
• Alliance: Adck2^{tm1.1(KOMP)Vlcg} page
• IMPC: Adck2 gene page

Mutation origin

• Mutant Cell Line: 12053A-G2
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 13219bp between positions 39524303-39537521 of Chromosome 6 (Genome Build37), and subsequent Cre-medated excision removed the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:	58 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Adck2 Mutation: 26 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)