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Mrap2tm1.1Maj
Targeted Allele Detail
Summary
Symbol: Mrap2tm1.1Maj
Name: melanocortin 2 receptor accessory protein 2; targeted mutation 1.1, Joseph A Majzoub
MGI ID: MGI:5526063
Synonyms: Mrap2-
Gene: Mrap2  Location: Chr9:87026359-87066098 bp, + strand  Genetic Position: Chr9, 46.76 cM
Alliance: Mrap2tm1.1Maj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:199365
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn FRT-flanked neomycin cassette in intron 3, along with loxP sites in intron 2 and 3' of Frt site were incorporated into the genome. Cre-mediated excision removed exon 3 and neomycin cassette. (J:199365)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mrap2 Mutation:  15 strains or lines available
References
Original:  J:199365 Asai M, et al., Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity. Science. 2013 Jul 19;341(6143):275-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory