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Hif1atm3.1Rsjo
Targeted Allele Detail
Nomenclature
Symbol: Hif1atm3.1Rsjo
Name: hypoxia inducible factor 1, alpha subunit; targeted mutation 3.1, Randall S Johnson
MGI ID: MGI:5525150
Gene: Hif1a  Location: Chr12:73901375-73947530 bp, + strand  Genetic Position: Chr12, 31.99 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202737
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination using mice carrying Gt(ROSA)26Sortm16(cre)Arte removed exon 2 from Hif1atm3Rsjo mice (J:202737)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hif1a Mutation:  11 strains or lines available
References
Original:  J:202737 Arsenault PR, et al., A Knock-in Mouse Model of Human PHD2 Gene-associated Erythrocytosis Establishes a Haploinsufficiency Mechanism. J Biol Chem. 2013 Nov 22;288(47):33571-84
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory