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Slc4a11tm1.1Jrcy
Targeted Allele Detail
Nomenclature
Symbol: Slc4a11tm1.1Jrcy
Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11; targeted mutation 1.1, Joseph R Casey
MGI ID: MGI:5524270
Gene: Slc4a11  Location: Chr2:130526033-130539439 bp, - strand  Genetic Position: Chr2, 63.24 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202267
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 9 through 13 were floxed. Cre-mediated recombination removed exons 9 through 13. Immunohistochemistry confirmed the absence of protein expression in the cornea. (J:202267)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc4a11 Mutation:  30 strains or lines available
References
Original:  J:202267 Vilas GL, et al., Transmembrane water-flux through SLC4A11: a route defective in genetic corneal diseases. Hum Mol Genet. 2013 Nov 15;22(22):4579-90
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory