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Tg(SFTPC-EZR/ROS1)AShiba
Transgene Detail
Nomenclature
Symbol: Tg(SFTPC-EZR/ROS1)AShiba
Name: transgene insertion A, Tatsuhiro Shibata
MGI ID: MGI:5523925
Synonyms: TgA
Transgene: Tg(SFTPC-EZR/ROS1)AShiba  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(SFTPC-EZR/ROS1)AShiba expresses 2 genes
 
Mutation detailsThe FLAG-tagged human fusion EZR/ROS1 cDNA (isolated from LCY66 tumor cDNA) is under the control of a type 2 alveolar epithelium-specific human surfactant protein C gene promoter. Line A harbors approximately four copies of the transgene. Two lines were generated, A and B. (J:199415)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:199415 Arai Y, et al., Mouse model for ROS1-rearranged lung cancer. PLoS One. 2013;8(2):e56010
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory