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Asah1tm1.1Jhkh
Targeted Allele Detail
Nomenclature
Symbol: Asah1tm1.1Jhkh
Name: N-acylsphingosine amidohydrolase 1; targeted mutation 1.1, Johannes Kornhuber
MGI ID: MGI:5523898
Gene: Asah1  Location: Chr8:41340197-41374773 bp, - strand  Genetic Position: Chr8, 23.89 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:199833
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was floxed and an FRT-lanked neomycin resistance cassette was inserted into the locus. Cre-mediated recombination removed exon 1. (J:199833)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Asah1 Mutation:  10 strains or lines available
References
Original:  J:199833 Gulbins E, et al., Acid sphingomyelinase-ceramide system mediates effects of antidepressant drugs. Nat Med. 2013 Jul;19(7):934-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory