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Mgat5btm1Nta
Targeted Allele Detail
Nomenclature
Symbol: Mgat5btm1Nta
Name: mannoside acetylglucosaminyltransferase 5, isoenzyme B; targeted mutation 1, Naoyuki Taniguchi
MGI ID: MGI:5523679
Gene: Mgat5b  Location: Chr11:116918863-116986948 bp, + strand  Genetic Position: Chr11, 81.49 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:199165
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exon 10. Enzymatic assay confirmed the absence of N-acetylglucosaminyltransferase-IX activity in brain microsomal fractions. (J:199165)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mgat5b Mutation:  52 strains or lines available
References
Original:  J:199165 Kanekiyo K, et al., Loss of branched O-mannosyl glycans in astrocytes accelerates remyelination. J Neurosci. 2013 Jun 12;33(24):10037-47
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory