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Scn1atm1.1Kzy
Targeted Allele Detail
Nomenclature
Symbol: Scn1atm1.1Kzy
Name: sodium channel, voltage-gated, type I, alpha; targeted mutation 1.1, Kazuhiro Yamakawa
MGI ID: MGI:5521534
Synonyms: Scn1aKIdneo, SCN1AR1407X, Scn1aRX, Scn1aRX(-neo)
Gene: Scn1a  Location: Chr2:66270781-66440840 bp, - strand  Genetic Position: Chr2, 39.13 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:121969
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Nucleotide substitutions
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Scn1a Mutation:  5 strains or lines available
References
Original:  J:121969 Ogiwara I, et al., Na(v)1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation. J Neurosci. 2007 May 30;27(22):5903-14
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory