About   Help   FAQ
Egln1tm2.2Fsl
Targeted Allele Detail
Summary
Symbol: Egln1tm2.2Fsl
Name: egl-9 family hypoxia-inducible factor 1; targeted mutation 2.2, Frank Lee
MGI ID: MGI:5521471
Synonyms: Phd2-
Gene: Egln1  Location: Chr8:125635326-125676063 bp, - strand  Genetic Position: Chr8, 72.86 cM
Alliance: Egln1tm2.2Fsl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202737
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination using mice carrying Gt(ROSA)26Sortm16(cre)Arte removed exon 2 from Egln1tm2.1Fsl mice. (J:202737)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Egln1 Mutation:  21 strains or lines available
References
Original:  J:202737 Arsenault PR, et al., A Knock-in Mouse Model of Human PHD2 Gene-associated Erythrocytosis Establishes a Haploinsufficiency Mechanism. J Biol Chem. 2013 Nov 22;288(47):33571-84
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory