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Egln1tm2.2Fsl
Targeted Allele Detail
Nomenclature
Symbol: Egln1tm2.2Fsl
Name: egl-9 family hypoxia-inducible factor 1; targeted mutation 2.2, Frank Lee
MGI ID: MGI:5521471
Synonyms: Phd2-
Gene: Egln1  Location: Chr8:124908587-124949254 bp, - strand  Genetic Position: Chr8, 72.86 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202737
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination using mice carrying Gt(ROSA)26Sortm16(cre)Arte removed exon 2 from Egln1tm2.1Fsl mice. (J:202737)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Egln1 Mutation:  12 strains or lines available
References
Original:  J:202737 Arsenault PR, et al., A Knock-in Mouse Model of Human PHD2 Gene-associated Erythrocytosis Establishes a Haploinsufficiency Mechanism. J Biol Chem. 2013 Nov 22;288(47):33571-84
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory