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Cd19tm1.1Oao
Targeted Allele Detail
Summary
Symbol: Cd19tm1.1Oao
Name: CD19 antigen; targeted mutation 1.1, Owen A O'Connor
MGI ID: MGI:5521189
Synonyms: CD19CherryLuciferase
Gene: Cd19  Location: Chr7:126007622-126014061 bp, - strand  Genetic Position: Chr7, 69.01 cM, cytoband F3-F4
Alliance: Cd19tm1.1Oao page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202574
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsThe construct targeted to exon 2 contains a mCherry and luciferase fusion, polyadenylation sequence and floxed neomycin resistance cassette. Cre-mediated recombination removed the neomycin resistance cassette. (J:202574)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd19 Mutation:  56 strains or lines available
References
Original:  J:202574 Scotto L, et al., Development and characterization of a novel CD19CherryLuciferase (CD19CL) transgenic mouse for the preclinical study of B-cell lymphomas. Clin Cancer Res. 2012 Jul 15;18(14):3803-11
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory