Opn4^tm1.1Yau
Targeted Allele Detail

Summary

• Symbol: Opn4^tm1.1Yau
• Name: opsin 4 (melanopsin); targeted mutation 1.1, King-Wai Yau
• MGI ID: MGI:5520169
• Gene: Opn4 Location: Chr14:34312575-34322099 bp, - strand Genetic Position: Chr14, 20.83 cM, cytoband B
• Alliance: Opn4^tm1.1Yau page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:81604
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Tau-lacZ and a loxP-flanked pgk-neomycin cassette replace fragments of exons 1 and 9 and the intervening sequence. Cre-mediated recombination removed the neomycin cassette. (J:81604, J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Opn4 Mutation: 33 strains or lines available

References

• Original: J:81604 Hattar S, et al., Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity. Science. 2002 Feb 8;295(5557):1065-70
• All: 9 reference(s)