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Kirrel3tm1.1Jfcl
Targeted Allele Detail
Nomenclature
Symbol: Kirrel3tm1.1Jfcl
Name: kirre like nephrin family adhesion molecule 3; targeted mutation 1.1, Jean-Francois Cloutier
MGI ID: MGI:5517690
Gene: Kirrel3  Location: Chr9:34485848-35036315 bp, + strand  Genetic Position: Chr9, 18.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:198564
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA membrane associated EGFP (GFP-F) and self-excising neomycin resistance cassette replaced the endogenous 18 amino acid signal sequence in exon 1. The final allele lacks the neomycin resistance cassette. RT-PCR confirmed the absence of transcript expression in the brain, olfactory bulb and vomeronasal organ. (J:198564)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kirrel3 Mutation:  4 strains or lines available
References
Original:  J:198564 Prince JE, et al., Kirrel3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression. Development. 2013 Jun;140(11):2398-408
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory