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Tg(CTSG-RARA/ZBTB16)#Sjch
Transgene Detail
Nomenclature
Symbol: Tg(CTSG-RARA/ZBTB16)#Sjch
Name: transgene insertion, Sai-Juan Chen
MGI ID: MGI:5517433
Synonyms: RARalpha/PLZF
Transgene: Tg(CTSG-RARA/ZBTB16)#Sjch  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CTSG-RARA/ZBTB16)#Sjch expresses 2 genes
 
Mutation detailsThe human RARA/ZBTB16 fusion gene is under the control of the human cathepsin-G promoter. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:194312)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:194312 Jiao B, et al., 8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARalpha degradation. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3495-500
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory