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Tg(CTSG-ZBTB16/RARA)#Sjch
Transgene Detail
Nomenclature
Symbol: Tg(CTSG-ZBTB16/RARA)#Sjch
Name: transgene insertion, Sai-Juan Chen
MGI ID: MGI:5517398
Synonyms: hCG-PLZF-RARalpha, PLZF-RARalpha
Transgene: Tg(CTSG-ZBTB16/RARA)#Sjch  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CTSG-ZBTB16/RARA)#Sjch expresses 2 genes
 
Mutation detailsThe human ZBTB16/RARA fusion gene is under the control of the human cathepsin-G promoter. The pound symbol (#) is used because lines are pooled. Lines 31, 33, 34, 74, 153, and 23 were pooled and analyzed in J:55196. (J:55196)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:55196 Cheng GX, et al., Distinct leukemia phenotypes in transgenic mice and different corepressor interactions generated by promyelocytic leukemia variant fusion genes PLZF-RARalpha and NPM-RARalpha. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6318-23
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory