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Fktntm3.1Ttd
Targeted Allele Detail
Nomenclature
Symbol: Fktntm3.1Ttd
Name: fukutin; targeted mutation 3.1, Tatsushi Toda
MGI ID: MGI:5514346
Synonyms: fukutinlox
Gene: Fktn  Location: Chr4:53713998-53765785 bp, + strand  Genetic Position: Chr4, 28.74 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:198535
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neomycin resistance cassette and left exon 2 floxed. (J:198535)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fktn Mutation:  17 strains or lines available
References
Original:  J:198535 Kanagawa M, et al., Impaired viability of muscle precursor cells in muscular dystrophy with glycosylation defects and amelioration of its severe phenotype by limited gene expression. Hum Mol Genet. 2013 Aug 1;22(15):3003-15
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory