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Cnih2tm1.1Ran
Targeted Allele Detail
Summary
Symbol: Cnih2tm1.1Ran
Name: cornichon family AMPA receptor auxiliary protein 2; targeted mutation 1.1, Roger A Nicoll
MGI ID: MGI:5513017
Synonyms: Cnih2fl
Gene: Cnih2  Location: Chr19:5142896-5148549 bp, - strand  Genetic Position: Chr19, 4.24 cM
Alliance: Cnih2tm1.1Ran page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:197912
Parent Cell Line:  iTL BA1 (ES Cell)
Strain of Origin:  (C57BL/6NTac x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT- and loxP-flanked neomycin resistance cassette was inserted upstream of exon 2. A loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the neomycin resistance cassette and left exons 2 through 5 floxed. (J:197912)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cnih2 Mutation:  11 strains or lines available
References
Original:  J:197912 Herring BE, et al., Cornichon proteins determine the subunit composition of synaptic AMPA receptors. Neuron. 2013 Mar 20;77(6):1083-96
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory