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Igs1tm10(CAG-Bgeo,-Fzd6)Nat
Targeted Allele Detail
Nomenclature
Symbol: Igs1tm10(CAG-Bgeo,-Fzd6)Nat
Name: intergenic site 1; targeted mutation 10, Jeremy Nathans
MGI ID: MGI:5510967
Synonyms: Iis1tm10(CAG-Bgeo,-Fz6)Nat, Z/3HAFz6
Gene: Igs1  Location: unknown  Genetic Position: Chr11, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence, No functional change)
Mutation:    Insertion
 
Igs1tm10(CAG-Bgeo,-Fzd6)Nat expresses 1 gene
 
Mutation detailsThe following elements were inserted, in order into a region 2 kb 5' of the Ubb gene by targeted recombination: CMV enhancer/beta-actin promoter, loxP site, beta-geo, 3 stop transcription sites, loxP site, 3HA-Fzd6, rabbit beta-globin 3' UTR. The 3HA tag is inserted after the signal peptide and before the cysteine-rich domain of Fzd6. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Igs1 Mutation:  10 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory