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Chemically induced Allele Detail
Symbol: Crklsnoop
Name: v-crk avian sarcoma virus CT10 oncogene homolog-like; snoopy
MGI ID: MGI:5510713
Synonyms: 12WT-9, Crklsno
Gene: Crkl  Location: Chr16:17451987-17487434 bp, + strand  Genetic Position: Chr16, 10.82 cM
Craniofacial and skeletal mutants: (A-D) Fras1bfb, (E-G) Ift140cauli, (H-J) knyn, and (K-M) Crklsnoop homozygotes

Show the 1 phenotype image(s) involving this allele.

Strain of Origin:  C57BL/6JAnu
Allele Type:    Chemically induced (ENU)
Mutation:    Undefined
Mutation detailsThe molecular lesion is a T-to-C substitution in the Crkl gene, at position Chr16:17,452,790 (GRCm38). This nucleotide substitution resides 2 nucleotides downstream of exon 1. The mutant transcript is predicted to result in a loss of a putative splice donor and/or generation of additional exonic splice enhancers. Mutant embryos exhibit a loss of transcript expression compared to controls. (J:251775)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crkl Mutation:  5 strains or lines available
Original:  J:199856 Caruana G, et al., Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental disease. PLoS One. 2013;8(3):e55429
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory