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Zbtb7btm6.1Itan
Targeted Allele Detail
Nomenclature
Symbol: Zbtb7btm6.1Itan
Name: zinc finger and BTB domain containing 7B; targeted mutation 6.1, Ichiro Taniuchi
MGI ID: MGI:5506929
Synonyms: ThpokSfl
Gene: Zbtb7b  Location: Chr3:89377644-89393673 bp, - strand  Genetic Position: Chr3, 39.09 cM, cytoband A1-A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:195348
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, Modified regulatory region, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of the 5' silencer region and a floxed neo cassette was inserted immediately downstream. Transient cre expression removed the selection cassette from properly targeted ES cells leaving the silencer region flanked by loxP sites. (J:195348)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zbtb7b Mutation:  19 strains or lines available
References
Original:  J:195348 Tanaka H, et al., Epigenetic Thpok silencing limits the time window to choose CD4(+) helper-lineage fate in the thymus. EMBO J. 2013 Apr 17;32(8):1183-94
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/07/2020
MGI 6.14
The Jackson Laboratory