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Rpl13atm1.1Mazu
Targeted Allele Detail
Nomenclature
Symbol: Rpl13atm1.1Mazu
Name: ribosomal protein L13A; targeted mutation 1.1, Barsanjit Mazumder
MGI ID: MGI:5502322
Gene: Rpl13a  Location: Chr7:45125563-45128745 bp, - strand  Genetic Position: Chr7, 29.14 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:194920
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsOne loxP site was inserted in intron 1 and a neomycin resistance cassette flanked by both FRT sites and by loxP sites was inserted following exon8. Flp recombinase was then used to remove the selection cassette from properly targed mice. exons 2-8 were then flanked by loxP sites. (J:194920)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rpl13a Mutation:  7 strains or lines available
References
Original:  J:194920 Poddar D, et al., An extraribosomal function of ribosomal protein l13a in macrophages resolves inflammation. J Immunol. 2013 Apr 1;190(7):3600-12
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory