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Transgene Detail
Symbol: Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan
Name: transgene insertion, Maike Sander
MGI ID: MGI:5501130
Synonyms: CAG-Bgeo,-Nkx6.1,-eGFP, Nkx6.1OE
Transgene: Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan  Location: unknown  
Strain of Origin:  (BALB/c x C57BL/6)F1
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(CAG-Bgeo,-Nkx6-1,-EGFP)#Msan expresses 1 gene
Mutation detailsThe CAG promoter drives ubiquitous expression of the mouse cDNA and IRES-EGFP preceded by a floxed beta-geo cassette. Two founder lines were established. The pound symbol (#) is used when no line is specified and/or lines are pooled. Cre-mediated recombination is required to removed the beta-geo cassette and allow for over-expression of the cDNA. (J:163847)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:163847 Schaffer AE, et al., Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors. Dev Cell. 2010 Jun 15;18(6):1022-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory