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Lin28atm1.1Gqda
Targeted Allele Detail
Nomenclature
Symbol: Lin28atm1.1Gqda
Name: lin-28 homolog A (C. elegans); targeted mutation 1.1, George Q Daley
MGI ID: MGI:5500060
Gene: Lin28a  Location: Chr4:134003330-134018841 bp, - strand  Genetic Position: Chr4, 66.5 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:196313
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT flanked neo cassette with a 5' loxP site was inserted downstream of exon 2 via homologous recombination. Cre-mediated recombination removed exon 2. (J:196313)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lin28a Mutation:  62 strains or lines available
References
Original:  J:196313 Shinoda G, et al., Lin28a regulates germ cell pool size and fertility. Stem Cells. 2013 May;31(5):1001-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory