Phf2tm1.1Yima
Targeted Allele Detail
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Symbol: |
Phf2tm1.1Yima |
Name: |
PHD finger protein 2; targeted mutation 1.1, Yuuki Imai |
MGI ID: |
MGI:5496656 |
Synonyms: |
Phf2Z |
Gene: |
Phf2 Location: Chr13:48955226-49024361 bp, - strand Genetic Position: Chr13, 24.96 cM, cytoband A3-A4
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Alliance: |
Phf2tm1.1Yima page
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Germline Transmission: |
Earliest citation of germline transmission:
J:198329
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Parent Cell Line: |
M1/M-1 (ES Cell)
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Strain of Origin: |
(129 x C57BL/6)F1
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The construct targeted upstream of exon 6 contains (5' to 3') a loxP site, lacZ gene, FRT site, neomycin resistance cassette, loxP site and FRT site. An additional FRT site was inserted downstream of exon 6. Flp-mediated recombination removed the neomycin resistance cassette and exon 6 but left the lacZ gene intact. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts.
(J:198329)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Phf2 Mutation: |
45 strains or lines available
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Original: |
J:198329 Okuno Y, et al., Epigenetic regulation of adipogenesis by PHF2 histone demethylase. Diabetes. 2013 May;62(5):1426-34 |
All: |
1 reference(s) |
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