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Pkd2tm1Sia
Targeted Allele Detail
Summary
Symbol: Pkd2tm1Sia
Name: polycystin 2, transient receptor potential cation channel; targeted mutation 1, Shinichi Aizawa
MGI ID: MGI:5496378
Gene: Pkd2  Location: Chr5:104607316-104653685 bp, + strand  Genetic Position: Chr5, 50.68 cM
Alliance: Pkd2tm1Sia page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:195164
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 1 was replaced with (5' to 3') lox71 site, lacZ gene with polyadenylation sequence, FRT-flanked neomycin resistance cassette, loxP site and polyadenylation sequence. (J:195164)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pkd2 Mutation:  84 strains or lines available
References
Original:  J:195164 Takao D, et al., Asymmetric distribution of dynamic calcium signals in the node of mouse embryo during left-right axis formation. Dev Biol. 2013 Apr 1;376(1):23-30
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory