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Krt1tm1Tmm
Targeted Allele Detail
Nomenclature
Symbol: Krt1tm1Tmm
Name: keratin 1; targeted mutation 1, Thomas M Magin
MGI ID: MGI:5495252
Gene: Krt1  Location: Chr15:101845428-101850786 bp, - strand  Genetic Position: Chr15, 57.06 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:197699
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
 
Mutation detailsThe Hprt-mini cassette replaced exon 1, intron 1 and 415 bp of the 5' UTR. Western blot analysis confirmed the absence of protein in the skin. (J:200244)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Krt1 Mutation:  2 strains or lines available
References
Original:  J:197699 Wallace L, et al., Deletion of K1/K10 does not impair epidermal stratification but affects desmosomal structure and nuclear integrity. J Cell Sci. 2012 Apr 1;125(Pt 7):1750-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/17/2015
MGI 5.21
The Jackson Laboratory