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Cxcl12tm2.1Sjm
Targeted Allele Detail
Summary
Symbol: Cxcl12tm2.1Sjm
Name: C-X-C motif chemokine ligand 12; targeted mutation 2.1, Sean J Morrison
MGI ID: MGI:5486673
Synonyms: Cxcl12-dsRED, CXCL12-RFP
Gene: Cxcl12  Location: Chr6:117145496-117158328 bp, + strand  Genetic Position: Chr6, 54.81 cM, cytoband F1
Alliance: Cxcl12tm2.1Sjm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:194748
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
    A DsRedE2-polyA-Frt-Neo-Frt cassette was inserted into the second exon of Cxcl12. (J:194748)
Expression
In Mice Carrying this Mutation: 8 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cxcl12 Mutation:  24 strains or lines available
References
Original:  J:194748 Ding L, et al., Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches. Nature. 2013 Mar 14;495(7440):231-5
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory