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Slc29a4tm1Jowg
Targeted Allele Detail
Summary
Symbol: Slc29a4tm1Jowg
Name: solute carrier family 29 (nucleoside transporters), member 4; targeted mutation 1, Joanne Wang
MGI ID: MGI:5485154
Gene: Slc29a4  Location: Chr5:142678267-142708245 bp, + strand  Genetic Position: Chr5, 81.56 cM
Alliance: Slc29a4tm1Jowg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:195656
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced exons 3 through 7. Cell assay confirmed the product has no transport activity for organic cations and monoamines. (J:195656)
Generation of the Slc29a4tm1Jowg allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc29a4 Mutation:  35 strains or lines available
References
Original:  J:195656 Duan H, et al., Impaired monoamine and organic cation uptake in choroid plexus in mice with targeted disruption of the plasma membrane monoamine transporter (Slc29a4) gene. J Biol Chem. 2013 Feb 1;288(5):3535-44
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory