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Tg(tetO-Fbxl21*)11Jt
Transgene Detail
Nomenclature
Symbol: Tg(tetO-Fbxl21*)11Jt
Name: transgene insertion 11, Joseph S Takahashi
MGI ID: MGI:5484569
Synonyms: tetO::Psttm
Transgene: Tg(tetO-Fbxl21*)11Jt  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(tetO-Fbxl21*)11Jt expresses 1 gene
 
Mutation detailsA tetO promoter drives expression of a mouse Fbxl21 gene with a G to A mutation at nucleotide 787 resulting in a glycine to a glutamic acid mutation in amino acid 149 within the third leucine-rich repeat of the protein. (J:194037)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:194037 Yoo SH, et al., Competing E3 Ubiquitin Ligases Govern Circadian Periodicity by Degradation of CRY in Nucleus and Cytoplasm. Cell. 2013 Feb 28;152(5):1091-105
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory