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Gpr161tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Gpr161tm1Lex
Name: G protein-coupled receptor 161; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:5475126
Gene: Gpr161  Location: Chr1:165295789-165326745 bp, + strand  Genetic Position: Chr1, 72.64 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:193395
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neo cassette replaced most of exon 3 except for the first 44 bp via homologous recombination. (J:193395)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gpr161 Mutation:  16 strains or lines available
References
Original:  J:193395 Mukhopadhyay S, et al., The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell. 2013 Jan 17;152(1-2):210-23
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/31/2018
MGI 6.12
The Jackson Laboratory