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Neurod1tm1.1(Atoh7)Whk
Targeted Allele Detail
Nomenclature
Symbol: Neurod1tm1.1(Atoh7)Whk
Name: neurogenic differentiation 1; targeted mutation 1.1, William H Klein
MGI ID: MGI:5472139
Synonyms: Neurod1Atoh7HA3
Gene: Neurod1  Location: Chr2:79452637-79456636 bp, - strand  Genetic Position: Chr2, 47.58 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:194077
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence, Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxC2 flanked neo cassette in inverse orientation and an Atoh7 cDNA fused to 3 hemagglutinin epitope (HA) tags replaced the entire coding region via homologous recombination. Cre mediated recombination removed the neo cassette. (J:194077)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Neurod1 Mutation:  18 strains or lines available
References
Original:  J:194077 Mao CA, et al., Reprogramming amacrine and photoreceptor progenitors into retinal ganglion cells by replacing Neurod1 with Atoh7. Development. 2013 Feb 1;140(3):541-51
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory