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Targeted Allele Detail
Symbol: Hoxb2tm2.2Fmr
Name: homeobox B2; targeted mutation 2.2, Filippo M Rijli
MGI ID: MGI:5470287
Synonyms: Hoxb2del
Gene: Hoxb2  Location: Chr11:96351632-96354020 bp, + strand  Genetic Position: Chr11, 59.85 cM
Germline Transmission:  Earliest citation of germline transmission: J:193058
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsAn FRT-flanked neo cassette with a 3' loxP site was inserted into the intron downstream of the translation start codon. An additional loxP site was inserted downstream of the translation stop codon. Flp-mediated recombination removed the neo cassette and left most of the coding sequence floxed. Cre-mediated recombination removed most of the coding sequence. (J:193058)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb2 Mutation:  1 strain or line available
Original:  J:193058 Miguez A, et al., Opposing roles for Hoxa2 and Hoxb2 in hindbrain oligodendrocyte patterning. J Neurosci. 2012 Nov 28;32(48):17172-85
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory