About   Help   FAQ
Hoxb2tm2.2Fmr
Targeted Allele Detail
Nomenclature
Symbol: Hoxb2tm2.2Fmr
Name: homeobox B2; targeted mutation 2.2, Filippo M Rijli
MGI ID: MGI:5470287
Synonyms: Hoxb2del
Gene: Hoxb2  Location: Chr11:96351632-96354020 bp, + strand  Genetic Position: Chr11, 59.85 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:193058
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn FRT-flanked neo cassette with a 3' loxP site was inserted into the intron downstream of the translation start codon. An additional loxP site was inserted downstream of the translation stop codon. Flp-mediated recombination removed the neo cassette and left most of the coding sequence floxed. Cre-mediated recombination removed most of the coding sequence. (J:193058)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb2 Mutation:  1 strain or line available
References
Original:  J:193058 Miguez A, et al., Opposing roles for Hoxa2 and Hoxb2 in hindbrain oligodendrocyte patterning. J Neurosci. 2012 Nov 28;32(48):17172-85
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/26/2020
MGI 6.15
The Jackson Laboratory