About   Help   FAQ
The MGI survey is now closed.
Thanks for your support!
Tg(Pcp2-ATXN2*127Q)#Plt
Transgene Detail
Nomenclature
Symbol: Tg(Pcp2-ATXN2*127Q)#Plt
Name: transgene insertion, Stefan M Pulst
MGI ID: MGI:5467321
Synonyms: ATXN2Q127
Transgene: Tg(Pcp2-ATXN2*127Q)#Plt  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Pcp2-ATXN2*127Q)#Plt expresses 1 gene
 
Mutation detailsThe Purkinje cell-specific mouse promoter drives expression of a modified human cDNA with an expansion of the trinucleotide repeat to encode 127 glutamine residues. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:191127)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:191127 Hansen ST, et al., Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2. Hum Mol Genet. 2013 Jan 15;22(2):271-83
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/20/2015
MGI 5.21
The Jackson Laboratory