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Mybbp1atm1Fbla
Targeted Allele Detail
Summary
Symbol: Mybbp1atm1Fbla
Name: MYB binding protein (P160) 1a; targeted mutation 1, Francesco Blasi
MGI ID: MGI:5466388
Gene: Mybbp1a  Location: Chr11:72332181-72342594 bp, + strand  Genetic Position: Chr11, 44.29 cM
Alliance: Mybbp1atm1Fbla page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:191942
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neo cassette replaced exons 1 through 13 and part of exon 14. (J:191942)
Generation of the Mybbp1atm1Fbla allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mybbp1a Mutation:  50 strains or lines available
References
Original:  J:191942 Mori S, et al., Myb-binding protein 1A (MYBBP1A) is essential for early embryonic development, controls cell cycle and mitosis, and acts as a tumor suppressor. PLoS One. 2012;7(10):e39723
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory